The Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection has been updated! For a complete preview of key updates to the guidelines, please see What's New in the Guidelines.
Please send your comments with the subject line “Comments on Pediatric Antiretroviral Treatment Guidelines” to ContactUs@aidsinfo.nih.gov by February 26, 2014.
(Last updated:2/12/2014; last reviewed:2/12/2014)
In the United States, the vast majority of HIV-infected children are receiving combination antiretroviral therapy (cART), making treatment-experienced children the norm. Changes in the antiretroviral (ARV) regimen and other aspects of the management of treatment-experienced children can be organized into the following categories: (1) modifying ARV regimens in children on effective cART for simplification or improved adverse effect profile; (2) recognizing and managing ARV drug toxicity or intolerance (see Management of Medication Toxicity or Intolerance); (3) recognizing and managing treatment failure; and (4) considerations about interruptions in therapy.